SOLVED: Osmolarity and Osmotic Pressure The primary function of the kidneys is to maintain homeostasis through regulation of the fluid balance between the

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Osmolarity and Osmotic Pressure   The primary function of the kidneys is to maintain homeostasis through regulation of the fluid balance between the intracellular and extra-cellular compartments of the body. This is achieved through filtration of the blood, reabsorption of water and salts, and secretion. The concentration of solutes in the blood creates an osmotic pressure. Osmotic pressure is measured in milliosmoles (mOsM) and it can be defined as the potential pressure developed by a solution separated from pure water by a differentially permeable membrane. The higher the solute concentration of the solution, the greater its osmotic potential. Since water always moves down a concentration gradient, it will move into or out of the RBC based upon the solute concentration of the solution it is in. Blood normally has an osmolarity of approximately 300 mOsM. Solutions such as 0.9% NaCl (.155 M) have a similar osmotic concentration and may be added to the blood without consequence to the RBCs. Usually, solutions having an osmolarity within ten percent of 300mOsM will not cause any significant change to the RBC. The following equation shows how osmolarity is calculated.   Grams/liter X number of ions formed X 1000 = osmolarity in mOsM M.W.     Osmotic Pressure = Conc. (in mMoles) X No. of dissociated species (ions) X 19.3 mm Hg     Calculate the osmotic pressure of the following:     1. 0.9% NaCl solution. (M.W. = 58 grams)     2. 150 mMoles CaCl2 solution (M.W. = 111 grams)     3. 7% glucose solution (M.W. = 180 grams)     4. 1% MgCl2 (M.W. = 95.2 grams)     5. How would each of the above solutions affect a RBC? 

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SOLVED: Osmolarity and Osmotic Pressure The primary function of the kidneys is to maintain homeostasis through regulation of the fluid balance between the

  • Written in: 17-Oct-2019
  • Paper ID: 11490361
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Oct 17, 2019

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